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KMID : 0351219950270060529
Korean Journal of Infectious Diseases
1995 Volume.27 No. 6 p.529 ~ p.536
Acinetobacter Bacteremia : Its Clinical Characteristics and Therapeutic Relevance



Abstract
Background:
@EN Acinetobacter bacteremia is less common due to low level of the virulence and pathogenic properties. Recently, its clinical relevance is augmented as frequent gram-negative bacterial isolates associated with a large number of
immunocompromised
host,
invasive procedures, and increasing antibiotic resistance.
@ES Methods:
@EN To elucidate clinical significance of Acinetobacter bacteremia, we retrospectively reviewed clinical records of 29 patients who were isolated Acinetobacter species from biood culture at Soon Chun Hyang University Hospital during 5 years from
March
1990 to July 1994.
@ES Results:
@EN Twenty three out of 29 patients belonged to true infections, remaind six belonged to pseudobacteremia or contamination. The risk factors of Acinetobacter bacteremia were hospitalization, especially in ICU, invasive procedure, recent
operation,
and
recent antimicrobial use. The primary sites sites of secondary Acinetobacter bacteremia were respiratory tract(30%), wound and skin(17%), urinary tract(9%), and intravenous catheter(9%). Primary sites were unknown in 35% of the patients. In
antimicrobial susceptibility, the most susceptible agent is colistin(100%), and followed by ciprofloxacin(85%), aztreonam(80%), Acinetobacter were resistant to most aminoglycosides and cephalosporins.
@ES Conclusion:
@EN Acinetobacter bacteremia is no longer infrequent infection in hospita lized patients especially in immunocompromised patients as well as patients in intensive care units. The most common primary site of infection was respiratory tract.
Acinetobacter
isolates were resistant to multi-antimicrobial agents, especially aminogycosides and cephalosporins. However if treated with the proper antiniclobial agents, prognosis of Acinetobacter bacteremia would be favorable.
KEYWORD
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